In The Souls of Black Folk, W.E.B. Du Bois introduces double consciousness as a result of racial prejudice and oppression. Explained as a state of confliction felt by black Americans, Du Bois presents double consciousness as integral to understanding the black experience. Later philosophers question the importance of double consciousness to current race discussions, but this paper contends that double consciousness provides valuable insights into black and white relations. To do this, I will utilize the modern slang term, “Oreo,” to (...) highlight how a perceived incompatibility between blacks and whites could prevent America from achieving a greater unity. (shrink)

In The Souls of Black Folk, W.E.B. Du Bois introduces double consciousness as a result of racial prejudice and oppression. Explained as a state of confliction felt by black Americans, Du Bois presents double consciousness as integral to understanding the black experience. Later philosophers question the importance of double consciousness to current race discussions, but this paper contends that double consciousness provides valuable insights into black and white relations. To do this, I will utilize the modern slang term, “Oreo,” to (...) highlight how a perceived incompatibility between blacks and whites could prevent America from achieving a greater unity. (shrink)

Recent evidence shows that dynamic instability is the dominant mechanism for the assembly of pure tubulin in vitro and for the great majority of microtubules in the mitotic spindle and the interphase cytoplasmic microtubule complex. The basic concepts of this model provide a framework for future characterization of the molecular basis of spatial and temporal regulation of microtubule dynamics in the cell and the function of microtubule dynamics in motile processes such as chromosome movement.

Despite their diversity and ecological importance, many areas of the SAR—Stramenopila, Alveolata, and Rhizaria—clade are poorly understood as the majority of SAR species lack molecular data and only 5% of species are from well-sampled families. Here, we review and summarize the state of knowledge about the three major clades of SAR, describing the diversity within each clade and identifying synapomorphies when possible. We also assess the “dark area” of SAR: the morphologically described species that are missing molecular data. The majority (...) of molecular data for SAR lineages are characterized from marine samples and vertebrate hosts, highlighting the need for additional research effort in areas such as freshwater and terrestrial habitats and “non-vertebrate” hosts. We also describe the paucity of data on the biogeography of SAR species, and point to opportunities to illuminate diversity in this major eukaryotic clade. See also the video abstract here: https://youtu.be/_VUXqaX19Rw. Despite their diversity, abundance, and importance, fewer than 10% of the species within the SAR—Stramenopila, Alveolata, and Rhizaria—clade have been assessed using molecular tools. Only a small percentage of the molecular records contain information on ecology or have associate location data, indicating a tremendous dark area. (shrink)

Relational reasoning is a complex form of human cognition involving the evaluation of relations between mental representations of information. Prior studies have modified stimulus properties of relational reasoning problems and examined differences in difficulty between different problem types. While subsets of these stimulus properties have been addressed in separate studies, there has not been a comprehensive study, to our knowledge, which investigates all of these properties in the same set of stimuli. This investigative gap has resulted in different findings across (...) studies which vary in task design, making it challenging to determine what stimulus properties make relational reasoning—and the putative formation of mental models underlying reasoning—difficult. In this article, we present the Multidimensional Relational Reasoning Task, a task which systematically varied an array of stimulus properties within a single set of relational reasoning problems. Using a mixed-effects framework, we demonstrate that reasoning problems containing a greater number of the premises as well as multidimensional relations led to greater task difficulty. The MRRT has been made publicly available for use in future research, along with normative data regarding the relative difficulty of each problem. (shrink)

The writings of al-Ghazālī give the distinct impression that he was highly concerned with the threat the Ismailis and their doctrines posed. By his own admission, he wrote six separate treatises to refute and condemn them, most importantly his Faḍāʾiḥ al-bāṭiniyya, which he composed in the year 488h in the months prior to his renunciation of government service and departure from Baghdad. His attack focused on the doctrine known as taʿlīm, with its insistence on the unrivaled absolute authority of a (...) single infallible Imam. He had in mind the Alamut teaching by Ḥasan-i Ṣabbāḥ of a doctrine then widely advocated in the Abbasid–Seljuk East. Significantly, there is no sign of this term used in this manner in the western Fatimid domains either earlier or later. However, our knowledge of events in the career of Ḥasan and of his teachings come from much later sources and are in part legendary at best. Although the doctrine of taʿlīm was certainly implicit in Ismaili works long before, in this particular work al-Ghazālī directed his attentions squarely against a new teaching he encountered personally in his own time and place. But we know it otherwise primarily from accounts recorded much later, in particular al-Shahrastānī’s al-Milal wa-l-niḥal. (shrink)

The exact sectarian affiliation of Shahrastānī has long been a matter of serious debate. Was he possibly an adherent of the Ismaili cause? Considerable recent scholarship purports to establish a connection. The evidence consists of some off-handed remarks by his own contemporaries; what he himself has to say about the Ismailis in his Kitāb al-Milal wa-l-niḥal; and finally, a set of doctrines or analytical categories he uses in his later writings that were later adopted by Nizari Ismailis. However, an impartial (...) look at the evidence does not support the claim that Shahrastānī was himself in any significant way an Ismaili. (shrink)

Background The ethical use both of human and non-human animals in research is predicated on the assumption that it is of a high quality and its projected benefits are more significant than the risks and harms imposed on subjects. Yet questions remain about whether and how IRBs and IACUCs should consider the scientific value of proposed research studies.Methods We draw upon 45 interviews with IRB and IACUC members and researchers with oversight experience about their perceptions of their own roles in (...) reviewing the quality and value of scientific protocols. Interview transcripts were memoed to highlight specific findings, which were then used to identify key themes through an iterative process.Results IRB and IACUC members expressed broad trust in the need for and value of research, and they often assumed that protocols had social value or that prior review, especially when associated with funding, affirmed both the rigor and merit of those protocols. Some oversight members also took an explicit stance against scientific review by stating that such review is not within the regulatory mandates governing their parts in the oversight system. Yet other interviewees expressed uneasiness about the current paradigm for evaluating the quality and overall value of science, suggesting that IRB and IACUC members perceive gaps in the oversight systems.Conclusions These findings reveal many similarities in how IRB and IACUC members understand the roles and limitations of their respective oversight committees. We conclude with a discussion of how the lack of a clear mandate regarding scientific review within US federal regulations may undermine ethical engagement of whether human and animal research is scientifically justified, resulting in a “mission lapse” wherein no organizational body is clearly responsible for ensuring that the research being conducted has the potential to advance science and benefit society. (shrink)

In lieu of an abstract, here is a brief excerpt of the content:Philosophy and Rhetoric 35.2 (2002) 91-95 [Access article in PDF] From: A Symposium on Rhetoric, Writing, and Culture Jeffrey Walker For who does not know, except them, that the art of using letters is fixed and unchanging, so that we always use the same letters for the same purposes, but in the art of discourse the case is entirely the reverse? —Isocrates, Against the SophistsThe essays composing this (...) issue of Philosophy and Rhetoric are based on papers that originally were presented at a symposium on "Rhetoric, Writing, and Culture," sponsored by the Emory University Center for Teaching and Curriculum, Department of English, and Hightower Fund, in March 2001. The ostensible purpose of the symposium was to consider the double nature and status of rhetoric: on one hand, a hermeneutic/theoretical discipline with applications across the humanities (in the analysis of texts, events, culture, argumentative practices, ideologies, and so forth); and, on the other hand, a practical "art of discourse," a techne, whose central or distinctive application is the training of skilled writers and speakers. The former tends to be emphasized in contemporary rhetorical studies, while the latter is the most familiar (though not necessarily essential) characteristic of "classical" or ancient rhetoric. Likewise, we can connect these two orientations, respectively, with rhetorical cultural studies and with the teaching of writing, speaking, and communication in general. While the natural assumption is that these two orientations are mutually supporting, that is not always or necessarily the case. One can argue that the first pulls in the direction of "philosophy" (however that may be defined), while the second pulls in the direction of sheer technique—and at one time or another, each has been [End Page 91] open to criticism for its lack of attention to the other: philosophers are ineffective rhetoricians, and cannot intervene in the public sphere; orators are superficial thinkers, and practice an irresponsible, demagogic art of manipulation and domination. This tension goes all the way back to the first critiques of the sophists, and plays out through the entire history of rhetoric. The symposium's speakers, then, were asked to reflect, in any way that seemed suitable to them, on either or both aspects of rhetoric's double nature, and/or the relationships between them.A symposium, inevitably, as a rhetorical event, always takes its own somewhat unpredictable trajectory, as papers are produced and presented, and as the ensuing discussion unfolds. And the four essays presented here—Steven Mailloux on Frederick Douglass and the nineteenth-century American debate over slavery; Susan Wells on "double consciousness" in S. Weir Mitchell's account of the case of Mary Reynolds and W. E. B. Du Bois's The Souls of Black Folk; James L. Kastely on the discontinuity between the "philosophical" and "technical" halves of Plato's Phaedrus;and Richard Doyle on the strange intersection between the emergence of LSD and the evolution of biotechnological understandings of DNA—are all revisions and expansions of the original presentations, reflecting the contingencies of their invention and reinvention. Nevertheless, the original motives of the symposium are still in evidence.As different as these essays are, it can be said that one or two underlying themes run through them, and provide a reply to the original topic proposed for the symposium. Perhaps the keynote is what Mailloux describes as "rhetorical paths of thought": that is, the "migration" and "evolution" of topoi, figures, lines of arguments, bits of narratives, and rhetorical traditions themselves (or fragments of them?) "from one community to another... [and] from one cultural moment to the next," as Frederick Douglass takes in the rhetorical traditions, practices, tropes and arguments exemplified in the Columbian Orator, as well as Aristotle's arguments on slavery, and as they become enabling parts of his own rhetorical repertoire in the debate on abolition. In Wells's essay, this appears as the "refunctioning" or reworking of topoi, as the notion of "double consciousness" is adapted as part of a "new logic of scientific authority" in Mitchell's account of "split personality," and also as a way of understanding and performing public discourse and identity in... (shrink)

The complex mechanisms by which nonlinear classical conservative systems undergo a transition from quasiperiodic to chaotic behavior are now fairly well understood. This transition is associated with a breakdown of quasi-constants of motion (KAM surfaces). There is growing evidence that similar mechanisms may govern the behavior of quantum systems. While K-type mixing behavior has not yet been found, there does appear to be a transition associated with the destruction of a quantum quasi-constant of motion (quantum KAM states) which changes qualitatively (...) the spectrum of quantum systems. (shrink)

A multidisciplinary faculty committee designed a curriculum to shape biomedical graduate students into researchers with a high commitment to professionalism and social responsibility and to provide students with tools to navigate complex, rapidly evolving academic and societal environments with a strong ethical commitment. The curriculum used problem-based learning (PBL), because it is active and learner-centred and focuses on skill and process development. Two courses were developed: Scientific Professionalism: Scientific Integrity addressed discipline-specific and broad professional norms and obligations for the ethical (...) practice of science and responsible conduct of research (RCR). Scientific Professionalism: Bioethics and Social Responsibility focused on current ethical and bioethical issues within the scientific profession, and implications of research for society. Each small-group session examined case scenarios that included: (1) learning objectives for professional norms and obligations; (2) key ethical issues and philosophies within each topic area; (3) one or more of the RCR instructional areas; and (4) at least one type of moral reflection. Cases emphasised professional standards, obligations and underlying philosophies for the ethical practice of science, competing interests of stakeholders and oversight of science (internal and external). To our knowledge, this is the first use of a longitudinal, multi-semester PBL course to teach scientific integrity and professionalism. Both faculty and students endorsed the active learning approach for these topics, in contrast to a compliance-based approach that emphasises learning rules and regulations. (shrink)

Background Residual dried blood spots (rDBS) from newborn screening programmes represent a valuable resource for medical research, from basic sciences, through clinical to public health. In Hong Kong, there is no legislation for biobanking. Parents’ view on the retention and use of residual newborn blood samples could be cultural-specific and is important to consider for biobanking of rDBS. Objective To study the views and concerns on long-term storage and secondary use of rDBS from newborn screening programmes among Hong Kong Chinese (...) parents. Methods A mixed-method approach was used to study the views and concerns on long-term storage and secondary use of rDBS from newborn screening programmes among Hong Kong Chinese parents of children 0–3 years or expecting parents through focus groups (8 groups; 33 participants) and a survey (n = 1012, 85% mothers) designed with insights obtained from the focus groups. We used framework analysis to summarise the themes as supportive factors, concerns and critical arguments for retention and secondary use of rDBS from focus group discussion. We used multiple logistic regression to assess factors associated with support for retention and secondary use of rDBS in the survey. Results Both in focus groups and survey, majority of parents were not aware of the potential secondary use of rDBS. Overall secondary use of rDBS in medical research was well accepted by a large proportion of Hong Kong parents, even if all potential future research could not be specified in a broad consent. However parents were concerned about potential risks of biobanking rDBS including leaking of data and mis-use of genetic information. Parents wanted to be asked for permission before rDBS are stored and mainly did not accept an “opt-out” approach. The survey showed that parents born in mainland China, compared to Hong Kong born parents, had lower awareness of newborn screening but higher support in biobanking rDBS. Higher education was associated with support in rDBS biobanking only among fathers. Conclusion Long-term storage and secondary use of rDBS from newborn screening for biomedical research and a broad consent for biobanking of rDBS are generally acceptable to Hong Kong parents given their autonomy is respected and their privacy is protected, highlighting the importance of an accountable governance and a transparent access policy for rDBS biobanks. (shrink)

Ordo V comprises works on religious instruction. This first volume of Ordo V in the Amsterdam edition of the Latin texts of Erasmus offers one of Erasmus’ earliest writings De contemptu mundi and other theological works, including the Explanation on the Apostles’ Creed , a book on prayer and a work on the Christian’s preparation on death.

Alongside concerns for animal welfare, concerns for land, water, and climate are undermining established food identities in many parts of the world. In Aotearoa New Zealand, agrifood relations are bound tightly into national identities and the materialities of export dependence on dairying and agriculture more widely. Dairy/ing identities have been central to national development projects and the politics that underpin them for much of New Zealand’s history. They are central to an intransigent agrifood political ontology. For the last decade, however, (...) they have been challenged by the identity politics of ethical food consumption. This paper explores the ensuing contests and asks how they are reshaping agrifood identities. We draw on interviews with 15 participants in Aotearoa New Zealand who have made dietary transitions that reduce or exclude dairy products. Our aim is not to identify a new post-dairying identity or claim a reconfigured national identity, but to examine the collision of production-consumption values in the context of a dominant place-based food identity. We ask how participants navigate contradictory commitments to becoming ‘good environmental citizens’ whilst remaining ‘good national citizens’. The paper offers insights for examining similar struggles elsewhere and the potential to shift agrifood relations and undermine entrenched political ontologies through ethical food consumption values. (shrink)

This book is a clear, comprehensive guide to the philosophic and religious concepts of the world's outstanding philosophers. Here are the great thoughts and ideas of the Western mind, selected and explained with magnificent precision by an eminent scholar. It is an illuminating portrait of man's intellectual and moral struggle to understand the world and the meaning of human life and destiny. Plato Aristotle Augustine Aquinas Luther Descartes Kant Rousseau Marx Nietzsche.

The case method approach, effective in disciplines from business to law, forms the backbone of this classroom-proven work. Designed specifically for undergraduate courses this latest revision includes six topical new cases on issues such as gene therapy, national security, and the death penalty. The remaining cases have all been updated to keep the book contemporary with "real life" issues, for productive discussion and fruitful learning. Book jacket.